Jamie George limped off during Saracens’ 32-24 Champions League defeat at Castells with a hamstring problem that ruled him out of the Six Nations. An English prostitute has had a miserable week.

The England captain was replaced by club team-mate Maro Itoje after Steve Borthwick named his Six Nations squad on Tuesday The injury at StoneX Stadium puts his availability for the February 1 game against Ireland in doubt.

George came on for two tries in the 55th minute, replacing front row Theo Dan, but was forced off in the closing stages as Saracens could not indicate the extent of the damage.

“Jamie has a hamstring injury. We’re not quite sure at the moment how serious the hamstring is,” director of rugby Mark McCall said.

George’s late withdrawal and Toby Knight’s serious knee injury made for a frustrating afternoon in north London as Castells finally secured victory after 21 straight away defeats in the Champions League.

The defeat was devastating for Saracens as they lost their last-16 home tie and must now travel to face Toulon.

“We had a really bad performance. Castells totally deserved to win the game and we got what we deserved, which is hard to say,” McCall said.

“For some reason our mentality wasn’t quite right and that’s on me and the coaches. It was a really disappointing day. Castells was definitely more enthusiastic than us. They were really ready for the game. “

“We had a lot of possession, but we were poor on the ball and they defended us easily. Then when the opportunity presented itself, they attacked. It was a disappointing day.”

“All 15 players they brought in have played in the last five weeks, just not together.

“This isn’t a bunch of kids, these are real football players and we really try to communicate that to the team. We’re just not quite there yet mentally.”

Scotland captain Tupulotu also misses the Six Nations with a pectoral injury

Scotland head coach Gregor Townsend also faces a pre-Six Nations dilemma as key duo Sione Tupulotu and Scott Cummings develop injury problems ahead of the Championship game .

There are particular concerns over the fitness of captain Tuipulotu, who has injured his pectoral muscle, with Glasgow boss Franco Smith suggesting – but refusing to confirm – that he fears the centre-forward will be on the sidelines for an extended period of time.

The 27-year-old did not feature in Saturday’s Champions League defeat to Harlequin.

When asked after the game for an update on Tupulotu’s condition, Smith said: “He’s been evaluated. I don’t know the extent of the evaluation yet.

“I think he might have injured his pectoral muscle. It’s a weird injury. It’s just something that happened. We don’t doubt it, we just want to make sure it’s nothing serious. But we’ll have a clearer picture tomorrow. “

Asked how much of a blow it would be if Tuipulotu – widely expected to be part of the British and Irish Lions squad this summer – misses any or all of the Championship, Smith did not answer to dispel There are concerns about what the impactful defender will face. On the sidelines during.

“It’s not just the player himself, but as a person and a player in our environment, he brings a lot of confidence to the people around him,” he said.

“So, I think it would be a loss for everyone if the injury was that serious, but I still think there’s still enough time in the season for him to contribute, so I hope the injury isn’t that serious and long. .

“He will come into the Scotland camp and be managed by their medical team, so once we have clarity on the outcome, as a group, all communication will be completed.

“I’m just saying, I don’t know yet, let’s see how it plays out.”